Tnbc ferroptosis
Webb3 feb. 2024 · Ferroptosis is a new type of cell death that was discovered in recent years and is usually accompanied by a large amount of iron accumulation and lipid … Webb20 maj 2024 · The term ferroptosis refers to a peculiar type of programmed cell death (PCD) mainly characterized by extensive iron-dependent lipid peroxidation. Recently, …
Tnbc ferroptosis
Did you know?
Webb9 dec. 2024 · Purpose: Triple-negative breast cancer (TNBC) is an aggressive tumor with poor prognosis, it has higher recurrence and metastatic rates than other breast cancer … Webb2 jan. 2024 · Thus, targeted knockdown of ASCT2 inhibits GSH synthesis and induces ferroptosis mediated by the accumulation of intracellular redox stress . Cancer cells cannot survive in the absence of exogenous glutamine, and therefore exhibit “glutamine addiction”, which is orchestrated by the interaction between xCT and ASCT2 [ 4 , 40 , 49 ].
Webb12 apr. 2024 · Triple-negative breast cancer (TNBC) is the most aggressive molecular subtype of breast cancer. Curcumol, as a natural small molecule compound, has … WebbRationale: Ferroptosis, a newly identified form of regulated cell death, can be induced following the inhibition of cystine-glutamate antiporter system X C- because of the impaired uptake of cystine. However, the outcome following the accumulation of endogenous glutamate in lung adenocarcinoma (LUAD) has not yet been determined.
Webb11 apr. 2024 · The article reports on a study investigating the role of nerve growth factor (NGF) and its receptor, tropomyosin receptor kinase A (TrkA), in triple-negative breast cancer (TNBC). The authors found that TNBC-derived MDA-MB-231 and MDA-MB-453 cells express TrkA and release biologically active NGF, which positively affects the migration, …
Webb8 apr. 2024 · The overexpression of α v β 3 and α v β 5 integrins and elevated levels of NRP-1 in TNBC are exploited for iRGD to emerge as a potential candidate for anticipating effective therapeutic outcomes. To evaluate the effect of iRGD in breast cancer, the peptide was co-administered with cancer therapeutics as a free drug or nanotherapeutic or in …
WebbStudying ferroptosis and iron metabolism pre-and post-radiotherapy treatment in breast cancer patients . × Close Log In. Log in with Facebook Log in with Google. or. Email. Password. Remember me on this computer. or reset password. Enter the email address you signed up with and we'll email you a reset link. Need ... chance locus of controlWebb31 okt. 2024 · Ferroptosis is accompanied by a disturbance of intracellular iron ion current and a significant increase of reactive oxygen species (ROS) and lipid peroxidation, the latter of which in the inner cell membrane causes membrane damage, and ultimately prompts cell disintegration and death. harbor country dental new buffaloWebb2 apr. 2024 · Rigid Shell Decorated Nanodevice with Fe/H 2 O 2 Supply and Glutathione Depletion Capabilities for Potentiated Ferroptosis and Synergized Immunotherapy @article{2024RigidSD, title={Rigid Shell Decorated Nanodevice with Fe/H 2 O 2 Supply and Glutathione Depletion Capabilities for Potentiated Ferroptosis and Synergized … chance love after lockup last nameWebb3 juni 2024 · Ferroptosis is a non-apoptotic form of cell death driven by excessive lipid peroxidation, which was involved in the pathogenesis, development as well as therapeutic targets of multiple types of cancer including triple-negative breast cancer (TNBC) [ 3, 4 ]. harbor country day school calendarWebb20 maj 2024 · Introduction. Ferroptosis is a newly identified type of iron-dependent programmed cell death that was first reported by Dixon et al in 2012. 1 As a new type of … chancellor zahawiWebb9 okt. 2024 · Ferroptosis is a non-apoptotic form of cell death that is induced by excessive lipid peroxidation, which provide an innovative way to combat cancer. Emerging … harbor country dental new buffalo miWebb13 apr. 2024 · HIGHLIGHTS who: Xiao-Fen Li from the Department of Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China have published the article: An iron metabolism and immune related gene signature … An iron metabolism and immune related gene signature for the prediction of clinical outcome and molecular … chance long band