Cisplatin hyponatremia

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August undefined, 2024

WebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis … WebFeb 16, 2024 · Hyponatremia, defined as a plasma sodium concentration lower than 135mmol/L, is the most common electrolyte disorder found in hospitalized patients.1 Its …

Cisplatin induced hyponatremia; looking deeper - Renal …

WebApr 7, 2024 · Acute overdosage of spironolactone tablets may be manifested by drowsiness, mental confusion, maculopapular or erythematous rash, nausea, vomiting, dizziness, or diarrhea. Rarely, instances of hyponatremia, hyperkalemia, or hepatic coma may occur in patients with severe liver disease, but these are unlikely due to acute overdosage. florence airport italy hotel

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WebRisk Factors for Severe Hyponatremia Related to Cisplatin: A Retrospective Case-Control Study. Onset of severe hyponatremia following cisplatin (CDDP) administration … WebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management. Platinum chemotherapy, particularly cisplatin, is commonly associated … WebSep 1, 2024 · Cisplatin for injection has been administered at 20 mg/m 2 intravenously daily for 5 days per cycle. Other doses and combination regimens have been used. ... other electrolyte abnormalities (hypocalcemia, hyponatremia, hypokalemia, and hypophosphatemia), Syndrome of Inappropriate Antidiuretic Hormone Excretion … florence alabama marketplace trucks

Chapter 5: Electrolyte and Acid Base Disorders in Malignancy

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WebJul 1, 2008 · Hyponatremia associated with platinum compounds is described more frequently with cisplatin than with carboplatin. 42, 43 The possible underlying pathophysiological mechanisms by which cisplatin induces hyponatremia are SIADH and renal salt wasting. 44 Cisplatin-induced hyponatremia often is combined with … WebKeywords: Cisplatin, Dehydration, Hyponatremia, Renal salt wasting, Siadh. Case Presentation: A 63-year-old male presents to the hospital with complaints of one-day history of weakness, dizziness. His outpatient blood work demonstrated a serum sodium level of 124 mEq/L, and a creatinine of 3.1 mg/dL. His medical history was significant for high ... florence alabama flea marketWebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are common side effects of platinum … florence alabama to bethesda tn

"WebJan 1, 2024 · Hyponatremia in cancer patients can be caused by a number of factors including gastrointestinal losses, cardiac failure, diabetes insipidus, cancer-induced … " - Cisplatin hyponatremia

Cisplatin hyponatremia

A Review of Drug-Induced Hyponatremia - ScienceDirect

WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose … WebNational Center for Biotechnology Information

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WebNational Center for Biotechnology Information WebWe report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated …

WebApr 12, 2024 · AKI-related cisplatin may also be associated with tubulopathies, such as Fanconi-like syndrome, hypomagnesemia, salt-loosing syndrome and distal renal tubular acidosis . Tubular dysfunction is characterized by electrolyte disorders such as hyponatremia, hypokalemia and hypomagnesemia. WebMay 17, 2024 · Hyponatremia occurs when the concentration of sodium in your blood is abnormally low. Sodium is an electrolyte, and it helps regulate the amount of water that's in and around your cells. In hyponatremia, one or more factors — ranging from an underlying medical condition to drinking too much water — cause the sodium in your body to …

WebDec 3, 2014 · We retrospectively investigated the incidence of hyponatremia in patients receiving brand-name cisplatin (CDDP) and a generic counterpart thereof. Methods: We … WebOnset of severe hyponatremia following cisplatin (CDDP) administration has been previously reported. However, the risk factors associated with hyponatremia still remain unclear. We conducted a retrospective, single-center, case-control study to identify independent risk factors of severe hyponatremia in patients with various types of cancers.

WebSep 1, 2002 · Other clinical features of cisplatin nephrotoxicity include hypomagnesemia, Fanconi-like syndrome (glucosuria, phosphaturia, and aminoaciduria), renal-salt wasting, and chronic renal failure....

WebJul 22, 2024 · Cisplatin-induced kidney toxicity is reviewed here. The use of cisplatin in patients with pre-existing kidney dysfunction and the kidney effects of the platinum … florence alabama breweryWebmostly solid tumors had hyponatremia, and of these, 11% had moderate (sodium [Na] 120–129 mEq/L) to severe (Na , 120 mEq/L) hyponatremia (1). This is disproportionately higher than the hyponatremia prevalence rates of 15%–30% reported for general medicine admissions (2). In cancer patients with nonsolid tumors, rates of hyponatremia are less. great southern bank blacktown nswWebhyponatremia was reported in 15% and 30.7% of 79 patients receiving brand and generic cisplatin respectively [16]. In our larger cisplatin treated cohort (n=298), all degree hyponatremia and moderate to severe hyponatremia was observed in 14.1% and 10% of patients respectively. In line with previous reports, hyponatremia was also florence alabama vicky whiteWebSep 15, 2024 · SIDE EFFECTS. Nephrotoxicity - Dose-related and cumulative renal insufficiency is the major dose-limiting toxicity of cis-platin.Renal toxicity has been noted in 28% to 36% of patients treated with a single dose of 50 mg/m 2.It is first noted during the second week after a dose and is manifested by elevations in BUN and creatinine, serum … great southern bank borrowing powerWebMay 22, 2012 · The development of hyponatremia during cisplatin therapy bears special mention. Cisplatin stimulates AVP secretion to cause SIADH, but it can also directly damage renal tubules to interfere with sodium reabsorption, which in rare cases may lead to hyponatremia via salt wasting nephropathy [ 41 ]. florence al elder lawyersWebProfound hyponatremia and dehydration: A case of cisplatin induced renal salt wasting syndrome 1 INTRODUCTION. Cis-diamminedichloroplatinum (CDDP), commonly known … florence al phone prefixWebFeb 16, 2024 · Cisplatin Dosage Medically reviewed by Drugs.com. Last updated on Feb 16, 2024. Applies to the following strengths: 50 mg; 10 mg; 1 mg/mL Usual Adult Dose for: Testicular Cancer Ovarian Cancer Bladder Cancer Usual Pediatric Dose for: Testicular Cancer Ovarian Cancer Bladder Cancer Additional dosage information: Renal Dose … florence alabama police department website