Circrhot1

Author: yeix

August undefined, 2024

WebHCC cells were infected with CRISPR/Cas Lentivirus containging circRHOT1-sgRNAs. circRHOT1-deficient HCC cells were screened out. Growth protocol HCC cells were cultured in DMEM medium supplemented with 20 % FBS, 2 mM glutamine, 1 mM pyruvate, 10 mM HEPES, 100 units/mL penicillin/streptomycin, 0.1 mg/mL gentamicin, and 2 g/L … WebFigure 1. CircRHOT1 is enhanced in clinical NSCLC samples and NSCLC cell lines. (A) The expression of circRHOT1 was analyzed by qPCR in clinical NSCLC tissues (n = 60) and peri-tumor tissues (n = 60).(B) The expression of circRHOT1 was measured by qPCR in the indicated cells.(C) The back-spliced and canonical forms of RHOT1 expression was …

Circular RNA circRHOT1 promotes hepatocellular …

Web(a) circRHOT1 level in BC cell lines detected by qRT-PCR. (b, c) circRHOT1 and RHOT1 mRNA expression measured by qRT-PCR in HT-1376 (b) and HTB9 (c) cells treated with RNase R or mock. WebcircRHOT1 and TIP60. RNA-sequencing method was used to analyze the downstream target gene of circRHOT1. Results: We identified circRHOT1 (hsa_circRNA_102034) as … on wolf\u0027s-head

Circular RNA circRHOT1 promotes hepatocellular carcinoma …

WebCircRHOT1 represses autophagy and in the OA rat model. (a)–(e) The OA rat model was constructed by receiving ACLT, and the OA rats were treated with circRHOT1 shRNA. (a) The expression of... WebDownload scientific diagram circRHOT1 knockout suppresses HCC cell proliferation, migration and invasion but promotes apoptosis. a The expression of circRHOT1 was analyzed by qRT-PCR in ... iou 0.50:0.95 area all maxdets 100

Circular RNA RHOT1 promotes progression and inhibits …

Circular RNA RHOT1 Regulates miR-142-5p/CCND1 to …

WebMar 3, 2024 · Moreover, circRHOT1 has been reported to promote cancer progression in multiple cancer models, such as liver cancer and pancreatic cancer [ 14, 15 ]. It has been identified that circRHOT1 is abnormally expressed in the and promotes the proliferation, migration, and invasion, and inhibits apoptosis of cancer cells [ 15 ]. WebMar 15, 2024 · Several circRNAs have been identified as key modulators in HCC progression, including cSMARCA5, 12 circTRIM33-12, 13 and circRHOT1. 14 In addition, a growing number of studies have focused on the competitive inhibitory effect … on wo laneWebKnockdown of circRHOT1 expression significantly inhibited proliferation as well as invasion, and it promoted apoptosis of pancreatic cancer cells via the regulation of E2F3 through the targeting of miR-125a-3p.Conclusion: Taken together, our results demonstrated that circRHOT1 plays critical roles in regulating the biological functions of … on wolf mountain rd wakefield mi 49968

"WebAug 12, 2024 · Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression Abstract Background: Increasing evidence has revealed a close relationship between... " - Circrhot1

Circrhot1

WebNational Center for Biotechnology Information WebAug 18, 2024 · CircRHOT1 is involved in the modulation of cell invasion, apoptosis, and proliferation by targeting miR-125a-3p in pancreatic cancer cells [11]. CircRHOT1 is increased and contributes to cell invasion and proliferation of pancreatic cancer cells [12]. Our data showed that circRHOT1 was elevated in clinical NSCLC samples and NSCLC …

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WebCircRHOT1 promotes the tumor growth of breast cancer in vivo. (A-E) The effect of circRHOT1 on tumor growth of breast cancer cells in vivo was analyzed by nude mice tumorigenicity assay by... WebCircRHOT1 enhances CCND1 expression by sponging miR-142-5p to inhibit chondrocyte autophagy and promote chondrocyte proliferation in OA [143]. Circ_0005526 promotes IL-1β-induced chondrocyte ...

WebNovel therapeutic strategies for BC clinical intervention are therefore urgently needed now more than ever. circRHOT1 is a newly identiﬁed circRNA that plays a crucial role in multiple types of tumorigeneses. However, it remains unclear whether circRHOT1 plays a functional role in BC progression. WebFigure 1: Characterization of circRHOT1 in BC. (a) circRHOT1 level in BC cell lines detected by qRT-PCR. (b, c) circRHOT1 and RHOT1 mRNA expression measured by qRT-PCR in HT-1376 (b) and HTB9 (c) cells treated with RNase R …

WebMar 4, 2024 · For instance, Wang et al. found that the high expression of circRHOT1 was associated with poor prognosis of hepatocellular carcinoma (HCC), and confirmed that circRHOT1 promoted malignant progression of tumors , Liang et al. discovered a new circRNA from breast cancer tissues, named circBMPR2, and identified its role in … WebMar 3, 2024 · CircRHOT1 promotes proliferation and inhibits apoptosis of breast cancer cells. (A) The MDA-MB-231 cells were treated with control shRNA or circRHOT1 shRNA. The expression of circRHOT1 was measured by qPCR in the cells. (B–G) The MDA-MB-231 and T47D cells were treated with control shRNA or circRHOT1 shRNA.

WebJun 1, 2024 · CircRHOT1 is a recently spotted circular RNA that is upregulated in several cancers, mainly in hepatocellular carcinoma and pancreatic cancer. ( Zhang et al., 2024, Ling et al., 2024 ), and participates in the regulation of tumor cell proliferation and death ( Ling et al., 2024, Qu et al., 2024 ). Yet, the role of circRHOT1 in asthma is not clear.

WebNov 28, 2024 · Furthermore, overexpression of STAT3 and the use of a miR-106a-5p inhibitor reversed BC progression that was mediated by circRHOT1 knockdown and also increased the levels of ROS, iron, and Fe 2+. Taken together, this study suggests that circRHOT1 promotes BC progression via the miR-106a-5p/STAT3 axis . on wolf\u0027s-baneWebAug 18, 2024 · Circular RNAs (circRNAs) have been identified as a sort of critical regulator in cancer progression. In this study, we identities the epigenetic regulation function of circular RNA circRHOT1 in promoting NSCLC cell proliferation. We found that circRHOT1 were elevated in… View PDF Save to Library Create Alert Cite Figures from this paper … on wolf\u0027smilkWebMar 3, 2024 · The circRHOT1 knockdown notably increased the levels of reactive oxygen species (ROS), iron, and Fe2+in breast cancer cells. Mechanically, circRHOT1 was able to sponge microRNA-106a-5p (miR-106a-5p) and inhibited ferroptosis by down-regulating miR-106a-5p in breast cancer cells. iot yemen trackWebBackground: Lung cancer is a common malignant tumor around the world. Propofol has been found to play an anti-tumor role. Therefore, the purpose of this study is to clarify the role and underlying molecular mechanisms of Propofol in … iou abbr crosswordWebDec 9, 2024 · Novel therapeutic strategies for BC clinical intervention are therefore urgently needed now more than ever. circRHOT1 is a newly identified circRNA that plays a crucial role in multiple types of... io\u0027s footprintWebJun 1, 2024 · CircRHOT1 is a recently spotted circular RNA that is upregulated in several cancers, mainly in hepatocellular carcinoma and pancreatic cancer. (Zhang et al., 2024, … iou 0.50 area all maxdets 100WebJun 11, 2024 · Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression Mol. Canc. (2024) D.H. Bach et al. Circular RNAs in cancer Mol. Ther. Nucleic Acids (2024) Z. Peng The long noncoding RNA LINC00312 induces lung adenocarcinoma migration and vasculogenic mimicry through directly binding YBX1 Mol. … iou and dice